Sagging and thinning of skin is the visible result of a structural collapse within the dermal layer of skin during aging. The breakdown occurs when collagen and elastin fibers become less abundant, disordered, and fragmented. This decline is driven by a myriad of age-related factors, including decreased cellular production, chronic inflammation, glycation, cellular senescence (cells that stop dividing but won't die), and daily exposure to UV radiation and free radicals. As ou
